Loosing weight the 'cool way' by Professor Patrick Rensen

White adipose tissue (WAT) stores excess energy (lipids, fat) and Brown adipose tissue (BAT) dissipates the stored energy as heat. Research evaluated their different roles.

Over the years, studies demonstrated that mild cold (15C) activates brown adipose tissue effectively compared to simulant compounds like ephedrine or saline. The cold requires to be a non-shivering thermogenesis temperature.

This 2017 research explored BAT distribution on the human body, its distribution (pictured above in Red and Blue) and how to quantify both its volume and its metabolic activity.

There are numerous studies about obesity and weight loss. When brown adipose tissue protects against body fat accumulation, a research in 2013 examined the therapeutic side of BAT to fight human obesity.

In 2011, a publication examined glucose intake induced in BAT by cold and when activated by cold, BAT dissipates energy in a perfusion-dependent way, exhibiting new metabolic response from cold and brown adipose tissue.

Cardiovascular disease risk is higher with obesity, study investigated the role of Brown Adipose Tissue dysfunction in cardiovascular diseases.

There are new studies investigating Brown Fat and other diseases: BAT & osteoporosis and its relation on bone density ; relationship between the decline of brown fat with age and development of Alzheimers and treatment of cancer by activating brown fat (BAT activated with cold "competed" with cancer cells for glucose).